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Differential sensitivities of the subunits of mammalian ribonucleotide reductase to proteases, sulfhydryl reagents, and heat

โœ Scribed by Atsushi Sato; Joseph G. Cory


Book ID
115707179
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
672 KB
Volume
244
Category
Article
ISSN
0003-9861

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A sensitive and rapid method has been developed for studying the interactions of ribonucleotide homopolymers with isolated liver ribosomal subunits. Small amounts of ribosomal subunits are first immobilised on Millipore filters. The homopolymers are then allowed to interact with the ribosomes by slo