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Differential scanning calorimetric study of mixtures of cholesterol with phosphatidylserine or galactocerebroside

โœ Scribed by D. Bach

Book ID
103038121
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
354 KB
Volume
35
Category
Article
ISSN
0009-3084

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โœฆ Synopsis

The thermotropic behavior of mixtures of cholesterol with phosphatidylserine (PS) or galactocerebroside was investigated.

In PS/cholesterol mixtures at low cholesterol concentrations only one peak in the thermograms is obtained. At about Xchol = 0.3 another peak at higher temperatures is also seen, this peak stems from phase transition of almost pure cholesterol phase. However, increase of Xchol results in further incorporation of cholesterol into the mixture.

In galactocerebroside-cholesterol mixtures above Xchol 0.4, at least two domains differing in cholesterol content and thermotropic properties coexist.

In the presence of cholesterol even at 1 : 1 molar ratios the phosphatidylserine or galactocerebroside are still undergoing melting.

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