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Differential responsiveness of early- and late-passage endothelial cells to shear stress

✍ Scribed by Fabio A. Kudo; Bohdan Warycha; Peter J. Juran; Hidenori Asada; Desarom Teso; Faisal Aziz; Jared Frattini; Bauer E. Sumpio; Toshiya Nishibe; Charles Cha; Alan Dardik

Book ID
116215270
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
310 KB
Volume
190
Category
Article
ISSN
0002-9610

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## Abstract Most acute coronary events occur in the upstream region of stenotic atherosclerotic plaques that experience laminar shear stress (LSS) elevated above normal physiological levels. Many studies have described the atheroprotective effect on endothelial behavior of normal physiological LSS