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Differential gene responses in endothelial cells exposed to a combination of shear stress and cyclic stretch

✍ Scribed by Masahisa Toda; Kimiko Yamamoto; Nobutaka Shimizu; Syotaro Obi; Shinichiro Kumagaya; Takashi Igarashi; Akira Kamiya; Joji Ando


Book ID
118472510
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
448 KB
Volume
133
Category
Article
ISSN
0168-1656

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## Abstract Most acute coronary events occur in the upstream region of stenotic atherosclerotic plaques that experience laminar shear stress (LSS) elevated above normal physiological levels. Many studies have described the atheroprotective effect on endothelial behavior of normal physiological LSS