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Differential responses of old human cartilage explants to synovial- and mononuclear-cell factors

✍ Scribed by O. Huber-Bruning; B. Wilbrink; J. E. Vernooij; J. W. J. Bijlsma; W. Otter; J. Huber


Publisher
Springer
Year
1987
Tongue
English
Weight
808 KB
Volume
7
Category
Article
ISSN
0172-8172

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## Abstract Following experimental demyelination in rodents, oligodendrocyte precursor cells (OPCs) proliferate and differentiate into myelin‐producing oligodendrocytes which effect robust remyelination. In contrast, remyelination in multiple sclerosis, the major human demyelinating disease, is gen