Differential regulation of p21 by p53 an
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Yuxin Yin; Gregory Solomon; Chuxia Deng; J. Carl Barrett
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Article
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1999
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John Wiley and Sons
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English
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๐ 2 views
Oxidative stress to mammalian cells causes cellular damage and triggers inducible cellular responses leading to cell death by apoptosis. In this paper, we report that p53 was required for programmed cell death induced by oxidative stress in both mouse and human cells and that p53 transactivation was