๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Differential repair of O6-methylguanine in DNA of rat hepatocytes and nonparenchymal cells

โœ Scribed by Lewis, J. G.; Swenberg, J. A.

Book ID
109720252
Publisher
Nature Publishing Group
Year
1980
Tongue
English
Weight
464 KB
Volume
288
Category
Article
ISSN
0028-0836

No coin nor oath required. For personal study only.

๐Ÿ“œ SIMILAR VOLUMES

Differential inactivation of O6-methylgu
Differential inactivation of O6-methylguanine-dna methyltransferase activity by O6-arylmethylguanines
โœ Katsuyoshi Mineura; Masahito Fukuchi; Masayoshi Kowada; Isamu Terashima; Kohfuku ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 473 KB

Activity of 06-methylguanine-DNA methyltransferase (MGMT) is well related with drug resistance of tumor cells to chloroethylnitrosoureas (CENUs), because MGMT removes CENU-induced O6-alkyIguanines in DNA by accepting the alkyl group at a cysteine moiety. Inactivation of MGMT is a feasible way to ove