Differential regulation of PTEN expression by androgen receptor in prostate and breast cancers
โ Scribed by Wang, Y; Romigh, T; He, X; Tan, M-H; Orloff, M S; Silverman, R H; Heston, W D; Eng, C
- Book ID
- 109972826
- Publisher
- Nature Publishing Group
- Year
- 2011
- Tongue
- English
- Weight
- 856 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0950-9232
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๐ SIMILAR VOLUMES
## BACKGROUND. The purpose of this study was to determine the contribution of different transactivating regions of the androgen receptor (AR) to the induction of androgen-regulated promoters in poorly (PC3 cells) and well-differentiated (LNCaP cells) prostate cancer cell lines. METHODS. PC3 and LN
Although the androgen receptor (AR) has been detected by ligand-binding assays, there is little known about the expression and regulation of the AR gene in human breast-cancer cells. AR mRNA, measured by Northern analysis in 18 cell lines, was found to be expressed predominantly in oestrogen-and pro