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Differential regulation of M-CSF and IL-6 gene expression in monocytic cells

โœ Scribed by Harry de Wit; Mariet T. Esselink; M. Ruud Halie; Edo Vellenga

Book ID
114713533
Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
631 KB
Volume
86
Category
Article
ISSN
0007-1048

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Cells of U937, a human monocytic leukemia cell line, differentiate into macrophages by treatment with 12-o-tetradecanoylphorbol-13-acetate (TPA), whereas cells treated with 1a,25-dihydroxyvitamin D3 [1,25-(OH) 2 D 3 ] continue to grow without undergoing differentiation. When U937 cells were successi