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DIFFERENTIAL REGULATION OF INTERLEUKIN-17 AND INTERFERON-GAMMA PRODUCTION IN INFLAMMATORY BOWEL DISEASE

โœ Scribed by L. Rovedatti; A. Di Sabatino; T. Kudo; P. Biancheri; M. Sarra; G. Monteleone; G.R. Corazza; T.T. MacDonald

Book ID
119633051
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
208 KB
Volume
41
Category
Article
ISSN
1590-8658

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## Background: We previously demonstrated that in inflammatory bowel disease (IBD) there is enhanced production of interleukin (IL)-21, a cytokine that activates multiple pathways that sustain mucosal inflammation. However, the phenotype of IL-21-producing cells in IBD, and the cytokine(s) they cop