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Interferon-gamma is causatively involved in experimental inflammatory bowel disease in mice

✍ Scribed by R. Ito; M. Shin-Ya; T. Kishida; A. Urano; R. Takada; J. Sakagami; J. Imanishi; M. Kita; Y. Ueda; Y. Iwakura; K. Kataoka; T. Okanoue; O. Mazda


Book ID
108699467
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
354 KB
Volume
146
Category
Article
ISSN
0009-9104

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Interferon-gamma-expressing cells are a
✍ Massimiliano Sarra; Ivan Monteleone; Carmine Stolfi; Massimo Claudio Fantini; Pi πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 642 KB

## Background: We previously demonstrated that in inflammatory bowel disease (IBD) there is enhanced production of interleukin (IL)-21, a cytokine that activates multiple pathways that sustain mucosal inflammation. However, the phenotype of IL-21-producing cells in IBD, and the cytokine(s) they cop