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Differential regulation of human blood monocyte and alveolar macrophage inflammatory cytokine production by nitric oxide

โœ Scribed by Dinakar, Chitra; Malur, Anagha; Raychaudhuri, Baisakhi; Buhrow, Lisa T; Melton, Alton L; Kavuru, Mani S; Thomassen, Mary Jane

Book ID
124146805
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
171 KB
Volume
82
Category
Article
ISSN
1081-1206

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Reactive nitrogen intermediates, such as nitric oxide (NO), play an important role in host-defense and injury. Human astrocytes released abundant NO upon stimulation with the pro-inflammatory cytokine interleukin (IL)-lp, which was potentiated by interferon (1FN)-y and tumor necrosis factor (TNFI-a.