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Differential regulation of hepatic cytochrome P450 monooxygenases in streptozotocin-induced diabetic rats

✍ Scribed by Sindhu, Ram K.; Koo, Ja-Ryung; Sindhu, Kunal K.; Ehdaie, Ashkan; Farmand, Farbod; Roberts, Christian K.

Book ID
115513448
Publisher
Informa plc
Year
2006
Tongue
English
Weight
254 KB
Volume
40
Category
Article
ISSN
1071-5762

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The effects of long-term insulin-dependent diabetes on the enzymatic activities of hepatic cytochrome P450 isozymes were determined in rats rendered diabetic by the administration of streptozotocin and killed 4, 8, and 12 weeks following treatment. The 0-dealkylations of ethoxyresorufin and pentoxyr