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Differential regulation and roles of urocortins in human adrenal H295R cells

✍ Scribed by Kazunori Kageyama; Komaki Hanada; Toshihiro Suda


Book ID
116858282
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
827 KB
Volume
162
Category
Article
ISSN
0167-0115

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The focus on the refinement, reduction and replacement of animal use in toxicity testing requires the development of cell-based systems that mimic the effects of xenobiotics in human tissues. The human adrenocortical carcinoma cell line, H295R, has been proposed as a model for studies on adrenal ste