Differential protective effects of varying degrees of hypoxia on the cytotoxicities of etoposide and bleomycin
โ Scribed by Toshitada Yamauchi; Thomas A. Raffin; Phillip Yang; Branimir I. Sikic
- Publisher
- Springer
- Year
- 1987
- Tongue
- English
- Weight
- 542 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0344-5704
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Although the adverse effect of hypoxia on drug metabolism is well documented in subcellular systems, its effect on drug clearance by the intact liver has not been defined. This study was undertaken in the isolated perfused rat liver to examine the effects of acute hypoxia on the hepatic elimination
Exposure to ultraviolet B (UV-B) light is recognized to induce suppression of certain immune responses, particularly delayed hypersensitivity. However, its effect on cytotoxic T lymphocyte (CTL) activity, of major importance in the resistance to viruses and tumours, has not been assessed to the same
The effect of the degree of synchrony in the ruminal release of energy and nitrogen on microbial protein synthesis (MPS) was examined in cattle consuming grass silage (7.9 kg DM day ร1 ) and a supplement of 1 kg day ร1 of sucrose given as an intraruminal infusion. The sucrose was infused in three di
Abbreviations: MGMT, 06-methylguanine-DNA methyltransferase, also designated as 06-alkylguanine-DNA alkyltransferase (EC 2.1.1.63); CNUs, chloroethylnitrosoureas; ACNU, 1-(2-chloroethyl)-3-[(4-amino-2-methyl-5-pyrimidyl)-methyl]-l-nitrosourea; BCNU, 1,3-bis-(2-chloroethyl)-1-nitrosourea; CCNU, l-(2-