𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Protective effect of O6-methylguanine-DNA methyltransferase (MGMT) on the cytotoxic and recombinogenic activity of different antineoplastic drugs

✍ Scribed by Ilka Preuss; Rudolf Thust; Bernd Kaina


Publisher
John Wiley and Sons
Year
1996
Tongue
French
Weight
809 KB
Volume
65
Category
Article
ISSN
0020-7136

No coin nor oath required. For personal study only.

✦ Synopsis


Abbreviations: MGMT, 06-methylguanine-DNA methyltransferase, also designated as 06-alkylguanine-DNA alkyltransferase (EC 2.1.1.63); CNUs, chloroethylnitrosoureas; ACNU, 1-(2-chloroethyl)-3-[(4-amino-2-methyl-5-pyrimidyl)-methyl]-l-nitrosourea; BCNU, 1,3-bis-(2-chloroethyl)-1-nitrosourea; CCNU, l-(2-chloroethyl)-3-cyclohexyl-l-nitrosourea; HeCNU, l-(2-chloroethyl)-3-(2-hydroxyethyl)-l-nitrosourea