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Differential inhibition of neutrophil superoxide generation by nonsteroidal antiinflammatory drugs

✍ Scribed by James C. Gay; John N. Lukens; Denis K. English


Publisher
Springer
Year
1984
Tongue
English
Weight
731 KB
Volume
8
Category
Article
ISSN
0360-3997

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Neutrophils contain a collagenase that is stored in a latent form within the specific granule. With cellular activation, the latent enzyme is activated in association with the production of a variety of oxidants, including hypochlorous acid. We evaluated 4 nonsteroidal antiinflammatory drugs (NSAIDs