## Abstract An international randomized trial in Langerhans cell histiocytosis (LCH) has been initiated by the Histiocyte Society. This report reviews the rationale, design, and progress of LCH‐I, which compares etoposide (VP‐16) and vinblastine in the treatment of disseminated LCH. Data on the ris
Differential expression of markers in extensive and restricted Langerhans Cell Histiocytosis (LCH)
✍ Scribed by Ferenc KŐhalmi; János Strausz; Márta EgervÁry; György Szekeres; József TímáR
- Book ID
- 112932666
- Publisher
- Springer Netherlands
- Year
- 1996
- Tongue
- English
- Weight
- 630 KB
- Volume
- 2
- Category
- Article
- ISSN
- 1219-4956
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Central nervous system (CNS) manifestations of Langerhans cell histiocytosis (LCH) remain among the major enigmas of this puzzling disease. The Histiocyte Society therefore covened a workshop on CNS LCH at the time of its 1996 meeting in Vienna, Austria. Prof. H. Gadner and Dr. N. Grois undertook th
Background. Pediatric patients with Langerhans cell histiocytosis (LCH) may become refractory to conventional therapy or present with repeated recurrences over several years. Current therapeutic options such as prednisone, vinblastine, etoposide, and cyclosporine are associated with significant acut