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Differential expression of (dihydro)ceramide synthases in mouse brain: oligodendrocyte-specific expression of CerS2/Lass2

✍ Scribed by Ivonne Becker; Lihua Wang-Eckhardt; Afshin Yaghootfam; Volkmar Gieselmann; Matthias Eckhardt

Book ID
106099999
Publisher
Springer
Year
2007
Tongue
English
Weight
550 KB
Volume
129
Category
Article
ISSN
1432-119X

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To explore the feasibility of cell type-specific gene expression in oligodendrocytes as a possible therapeutic approach for demyelinating diseases, the cell specificity, tissue specificity, and duration of gene expression were investigated using recombinant adenoassociated viral vectors (rAAV) carry