A competitive polymerase chain reaction has been developed for quantitation of BRCA1 mRNA. In human cancer cell lines, the amount of BRCA1 mRNA is relatively low, ranging from 6 to 38 copies per cell. The decay rate of these transcripts in actinomycin-treated cells indicates that the half-life of th
Differential expression and subcellular localization of murine BRCA1 and BRCA1-δ11 isoforms in murine and human cell lines
✍ Scribed by Richard Bachelier; Nicole Dalla Venezia; Sylvie Mazoyer; Lucien Frappart; Gilbert M. Lenoir; Anne Vincent
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- French
- Weight
- 197 KB
- Volume
- 88
- Category
- Article
- ISSN
- 0020-7136
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
The copper complexes of 2-furaldehyde and furan oximes have previously demonstrated potent cytotoxicity, L1210 DNA synthesis inhibition, DNA topoisomerase II inhibition and DNA fragmentation. Currently a series of cobalt metal complexes of 2-furaldehyde oximes were compared with copper complexes of
Human SK-N-AS neuroblastoma and U-87MG glioblastoma cell lines were found to secrete relatively high levels of glial cell line-derived neurotrophic factor (GDNF). In response to growth factors, cytokines, and pharmacophores, the two cell lines differentially regulated GDNF release. A 24-hr exposure
## Characterization of the differential protein expression associated with thermoresistance in human gastric carcinoma cell lines Resistance to chemotherapeutic agents is one of the major problems faced during palliative therapy of tumor cells. Thus, chemotherapy is frequently combined with other
Cross-reaction between antibodies raised against the last 20 C-terminal amino acids