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Differential Effects of Wilms Tumor WT1 Splice Variants on the Insulin Receptor Promoter

✍ Scribed by Nicholas J.G. Webster; Yan Kong; Prem Sharma; Martin Haas; Saraswati Sukumar; B.Lynn Seely


Book ID
112238257
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
969 KB
Volume
62
Category
Article
ISSN
1077-3150

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The same mutation affecting the splicing
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Communicated by Michel Goossens ## Denys -Drash and Frasier syndromes are rare human disorders that associate nephropathy with gonadal and genital abnormalities. In DDS there is a predisposition to Wilms tumor. Heterozygous point mutations in the Wilms tumor, type1 gene (WT1), particularly those