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Differential effects of the calcium ionophore A23187 and the phorbol ester PMA on lymphocyte proliferation

✍ Scribed by D. Planelles; J. Hernández-Godoy; A. González-Molina

Publisher
SP Birkhäuser Verlag Basel
Year
1992
Tongue
English
Weight
518 KB
Volume
35
Category
Article
ISSN
1420-908X

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✍ Andrea M. Mastro; M. C. Smith 📂 Article 📅 1983 🏛 John Wiley and Sons 🌐 English ⚖ 702 KB

The phorbol ester tumor promoter 12-O-tetradecanoylphorbol-13-acetate (TPA) and the calcium ionophore, A23187, have similar effects on many different cells. For example, both show mitogenic and comitogenic activities for lymphocytes. It had been suggested that some of TPA's effects are due to its ab