Differential effects of proinsulin C-peptide fragments on Na +, K +-ATPase activity of renal tubule segments
✍ Scribed by Y. Ohtomo; T. Bergman; B.-L. Johansson; H. Jörnvall; J. Wahren
- Book ID
- 105821894
- Publisher
- Springer
- Year
- 1998
- Tongue
- English
- Weight
- 145 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0012-186X
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In vitro effects of six dibenzyltin dichloride (A-series) and another six dibenzyltin diisothiocyanate (Bseries) complexes on Na ؉ /K ؉ -ATPase were studied. The rat brain synaptic membranes were prepared and significant ATPase inhibition was observed with all the complexes in a dose-dependent manne
## Abstract ## Aims/Hypothesis C‐peptide reduces renal damage in diabetic patients and experimental animal models. __In vitro__ studies suggest that the renal effects of C‐peptide may, in part, be explained by stimulation of Na^+^/K^+^‐ATPase activity. However, the responses of Na^+^/K^+^‐ATPase e