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Differential Effects of Interleukin-12 and Interleukin-10 on Superantigen-Induced Expression of Cutaneous Lymphocyte-Associated Antigen and αEβ7 Integrin (CD103) by CD8+ T cells

✍ Scribed by H. Sigmundsdóttir; A. Johnston; J. E. Gudjónsson; H. Valdimarsson

Book ID: 110749552
Publisher: John Wiley and Sons
Year: 2008
Tongue: English
Weight: 259 KB
Volume: 59
Category: Article
ISSN: 0300-9475
DOI: 10.1111/j.0300-9475.2004.01423ab.x

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## Background: Intraepidermal t lymphocytes are a critical element for sustaining the lesional pathology of psoriasis. integrin alphaebeta7 (cd103), a ligand for e-cadherin, may play a role in the localization of pathogenic t cells within the epidermis of psoriatic lesions. however, little informat