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Differential Effects of Inflammatory Mediators on Ion Secretion in the Guinea-Pig Colon

✍ Scribed by Th Frieling; C Rupprecht; G Dobreva; M Schemann

Book ID
114215863
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
373 KB
Volume
118
Category
Article
ISSN
0300-9629

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Following i.v. injection of digoxin (1Opg kg-') the ratio between digoxin concentrations in the lumen ofjejunal loops perfused in situ and in plasma (L/P) of guinea pigs increased linearily with time. After 3 h, L/P was 8.7, indicating net secretion of digoxin against a concentration gradient. In qu