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Differential Effects of Ethanol on Serum GABAergic 3α,5α/3α,5β Neuroactive Steroids in Mice, Rats, Cynomolgus Monkeys, and Humans

✍ Scribed by Patrizia Porcu; Todd K. O’Buckley; Sarah E. Alward; Soomin C. Song; Kathleen A. Grant; Harriet De Wit; A. Leslie Morrow

Book ID: 109124487
Publisher: John Wiley and Sons
Year: 2010
Tongue: English
Weight: 597 KB
Volume: 34
Category: Article
ISSN: 0145-6008
DOI: 10.1111/j.1530-0277.2009.01123.x

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## Abstract The development and validation of liquid chromatography–electrospray ionization–tandem mass spectrometric (LC–ESI‐MS/MS) methods that enable the quantification of neuroactive androgens, androsterone (5__α__‐androstan‐3__α__‐ol‐17‐one, 3__α__,5__α__‐A) and 5__α__‐androstane‐3__α__,17__β_