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Differential effects of cyclooxygenase inhibitors on haloperidol-induced catalepsy

โœ Scribed by Pattipati S. Naidu; Shrinivas K. Kulkarni


Book ID
117448931
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
97 KB
Volume
26
Category
Article
ISSN
0278-5846

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Pretreatment with quipazine, a serotonin agonist, and clomipramine, a selective serotonin neuronal uptake blocker, was found to potentiate the cataleptic effect of haloperidol in a dose-dependent manner in rats. Pretreatment with methysergide, a serotonin antagonist, reduced the cataleptic effect of