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Differential effects of cimetidine, ranitidine and famotidine on the hepatic metabolism of estrogen and testosterone in male rats

✍ Scribed by Richard A. Galbraith; Peter H. Jellinck

Book ID
115781140
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
431 KB
Volume
38
Category
Article
ISSN
0006-2952

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Cimetidine and ranitidine absorption were studied in rats, alone or in combination with concurrent but separate bupropion oral admininstration. Blood samples were collected before and 0.25, 0.5, 0.75, 1.0, 1-5, 2.0, 3.0, 4.5, and 6.0 h after dosing. In ranitidinetreated rats, an exta blood sample at