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Differential effects of acute and repeated morphine treatment on κ-opioid receptor mRNA levels in mesocorticolimbic system

✍ Scribed by Gang, Yu; Hui, Yan; Ze-Hui, Gong


Book ID
122332901
Publisher
Elsevier
Year
2012
Tongue
English
Weight
109 KB
Volume
64
Category
Article
ISSN
1734-1140

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## Abstract We investigated whether acute treatment with agonists affected the subcellular distribution of κ opioid receptor (KOPR) in the dorsal horn of the rat lumbar spinal cord by using immunoelectron microscopy. Rats were injected intrathecally (i.t.) with U50,488H (100 nmole), dynorphin A(1–1