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Differential time course of effects of κ-opioid agonist treatment on dynorphin a levels and κ-opioid receptor density

✍ Scribed by Claudio D’Addario; Manuela Di Benedetto; Sari Izenwasser; Sanzio Candeletti; Patrizia Romualdi

Book ID
111639796
Publisher
Humana Press Inc
Year
2004
Tongue
English
Weight
158 KB
Volume
24
Category
Article
ISSN
0895-8696

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## Abstract We investigated whether acute treatment with agonists affected the subcellular distribution of κ opioid receptor (KOPR) in the dorsal horn of the rat lumbar spinal cord by using immunoelectron microscopy. Rats were injected intrathecally (i.t.) with U50,488H (100 nmole), dynorphin A(1–1