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Differential effects of acetaminophen pretreatment on hepatic aflatoxin B1-DNA binding, cellular proliferation, and aflatoxin B1-induced hepatic foci in rats and hamsters

โœ Scribed by Shingo Hiruma; Prathima Gopalan-Kriczky; Guozhong Qin; John P Gaughan; Prabhakar D Lotlikar


Book ID
117467015
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
100 KB
Volume
170
Category
Article
ISSN
0304-3835

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Effects of intermittent exposures of afl
โœ Saura C. Sahu; Ming W. Chou; Rene E. Sotomayor; Dennis M. Hinton; Curtis N. Bart ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 47 KB ๐Ÿ‘ 2 views

Glutathione S-transferase (GST) plays a major role in the detoxification of the potent hepatocarcinogen aflatoxin B(1) (AFB(1)). This study evaluated the effects of intermittent exposures to AFB(1) on hepatic and testicular GST in rats. Male Fischer 344 rats were fed diets containing AFB(1) (0, 0.01