## Abstract Glutamine, a byproduct of ammonia detoxification, is found elevated in brain in hepatic encephalopathy (HE) and other hyperammonemic disorders. Such elevation has been implicated in some of the deleterious effects of ammonia on the central nervous system (CNS). Recent studies have shown
Differential effect of pentobarbital on chick neurons and astrocytes grown in culture
โ Scribed by B. F. Roth-Schechter; G. Tholey
- Publisher
- Springer
- Year
- 1982
- Tongue
- English
- Weight
- 451 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0364-3190
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## Abstract Glutamate dehydrogenase (GDH) specific activities, kinetic properties and allosteric regulation were studied in extracts from cultured neurons and astrocytes prepared from mouse cerebral cortex and cerebellum. Considerable differences were observed in the specific activity of the enzyme
Brainstem pieces from the trigeminal region of the metencephalic basal plate of 10-day chick embryos were dissociated and cultured in control conditions or in the presence of muscle-conditioned medium (MCM). The MCM was derived from age-matched target tissue relevant to this neuronal region (jaw mus