Astroglial swelling occurs in acute hyperammonemic states, including acute hepatic encephalopathy. In these conditions, the peripheral-type benzodiazepine receptor (PBR), a receptor associated with neurosteroidogenesis, is up-regulated. This study examined the potential involvement of PBRs and neuro
Combined Effects of Ammonia and Manganese on Astrocytes in Culture
โ Scribed by A. R. Jayakumar; K. V. Rama Rao; P. Kalaiselvi; M. D. Norenberg
- Publisher
- Springer
- Year
- 2004
- Tongue
- English
- Weight
- 211 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0364-3190
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## Abstract Hepatic encephalopathy (HE) is a major neurological complication in patients with severe liver disease. While the pathogenesis of HE is unclear, elevated blood and brain ammonia levels are believed to be major etiological factors, and astrocytes appear to be the primary target of its to
The present study evaluates the physiological effects of magnetic stimulation on astrocyte cultures. Cell cultures were exposed to pulsed magnetic stimulation (10 Hz, 10 sec) at the following levels: 0.10 tesla (T; Group A); 0.21 T (Group B); 0.42 T (Group C); and 0.63 T (Group D). Glial fibrillary