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Differential Effect of Doxorubicin and Zoledronic Acid on Intraosseous versus Extraosseous Breast Tumor Growth In vivo

โœ Scribed by Ottewell, P. D.; Deux, B.; Monkkonen, H.; Cross, S.; Coleman, R. E.; Clezardin, P.; Holen, I.

Book ID
121675345
Publisher
American Association for Cancer Research
Year
2008
Tongue
English
Weight
708 KB
Volume
14
Category
Article
ISSN
1078-0432

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Sustained inhibition of tumor growth and
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โœ Penelope D. Ottewell; Diane V. Lefley; Simon S. Cross; C. Alyson Evans; Robert E ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 390 KB

## Abstract Combination therapy, using agents that target the microenvironment as well as the cancer cells, is common in the treatment of advanced breast cancer. Here, we show that a 6โ€week course of weekly sequential administration of the cytotoxic drug doxorubicin (2 mg/kg), followed 24 hr later