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Anticancer mechanisms of doxorubicin and zoledronic acid in breast cancer tumor growth in bone

โœ Scribed by Ottewell, P. D.; Woodward, J. K.; Lefley, D. V.; Evans, C. A.; Coleman, R. E.; Holen, I.

Book ID
118139872
Publisher
American Association for Cancer Research
Year
2009
Tongue
English
Weight
573 KB
Volume
8
Category
Article
ISSN
1535-7163

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๐Ÿ“œ SIMILAR VOLUMES

Sustained inhibition of tumor growth and
Sustained inhibition of tumor growth and prolonged survival following sequential administration of doxorubicin and zoledronic acid in a breast cancer model
โœ Penelope D. Ottewell; Diane V. Lefley; Simon S. Cross; C. Alyson Evans; Robert E ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 390 KB

## Abstract Combination therapy, using agents that target the microenvironment as well as the cancer cells, is common in the treatment of advanced breast cancer. Here, we show that a 6โ€week course of weekly sequential administration of the cytotoxic drug doxorubicin (2 mg/kg), followed 24 hr later