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Differential consequences of renal failure on the pharmacokinetics of Oxprenolol and its main metabolite

✍ Scribed by P. Dayer; Ph. Glasson; L. Balant; R. Striberni; J. Fabre


Book ID
113005923
Publisher
Springer-Verlag
Year
1983
Tongue
English
Weight
666 KB
Volume
8
Category
Article
ISSN
0378-7966

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The pharmacokinetics of 20 mg torasemide i.v. has been studied in 7 healthy controls and 9 patients with varying degrees of renal impairment. Torasemide had a t1/2 of about 4h which was independent of kidney function, as the nonrenal clearance of torasemide was 3-times greater than its renal clearan