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Differential binding of allolactose anomers to the lactose represser of Escherichia coli

✍ Scribed by Cheryl L. Turner; R.E. Huber


Book ID
118917911
Publisher
Elsevier Science
Year
1977
Tongue
English
Weight
365 KB
Volume
115
Category
Article
ISSN
0022-2836

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The conformationally sensitive epitope for monoclonal antibody (mAb) 4B1, which uncouples lactose from H+ translocation in the lactose permease of Escherichia coli, is localized in the periplasmic loop between helices VII and VIII (loop VII/VIII) on one face of a short helical segment (Sun J, et al.