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Different sensitivity of BALB/c 3T3 cell clones in the response to carcinogens

โœ Scribed by Annamaria Colacci; Maria Grazia Mascolo; Stefania Perdichizzi; Daniele Quercioli; Antonio Gazzilli; Francesca Rotondo; Elena Morandi; Angela Guerrini; Paola Silingardi; Sandro Grilli; Monica Vaccari

Book ID
116920484
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
405 KB
Volume
25
Category
Article
ISSN
0887-2333

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Intracellular acidification inhibits the
Intracellular acidification inhibits the proliferative response in BALB/c-3T3 cells
โœ C. A. Lucas; R. J. Gillies; J. E. Olson; K. A. Giuliano; R. Martinez; J. M. Snei ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 734 KB

One of the earliest events to occur upon the addition of serum to quiescent cells is an increase in the intracellular pH (pHin). The relationship between this pH change and proliferation is not known. In the present study, we investigate the consequences of acidifying the cytosol using the weak acid