Rat thymocytes of the T cell receptorlow (TcRIOW) CD4+8+ subset which is the target of repertoire selection are heterogeneous with respect to expression of the cell interaction (CI) molecules CD2, CD5, CDlldCD18 (LFA-l), CD28 and CD44. We show that this heterogeneity is due to the developmental regu
Different recognition of transgenic HLA-DQw6 molecules by mouse CD4+and CD8+T cells
✍ Scribed by Takeshi Inamitsu; Yasuharu Nishimura; Takehiko Sasazuki
- Publisher
- Springer-Verlag
- Year
- 1992
- Tongue
- English
- Weight
- 434 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0093-7711
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract ## Objective To investigate the molecular mechanism responsible for the reduced capacity of dendritic cells (DCs) from HLA–B27–transgenic rats to form conjugates with naive T cells. ## Methods We monitored interactions between DCs derived from HLA–B27–transgenic, HLA–B7–transgenic co
## Abstract We were the first to demonstrate that combined immunotherapy with GM‐CSF producing GL261 cells and recombinant IFNγ of preestablished GL261 gliomas could cure 90% of immunized mice. To extend these findings and to uncover the underlying mechanisms, the ensuing experiments were undertake