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Different reactivities of monoclonal antibodies to ganglioside lactones

โœ Scribed by Tadashi Tai; Ikuo Kawashima; Nobuhiko Tada; Shuji Ikegami

Book ID
115740074
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
906 KB
Volume
958
Category
Article
ISSN
0005-2760

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We generated 3 murine monoclonal antibodies (MAbs) specific for ganglioside lactones by immunizing C3H/HeN mice with purified lactones adsorbed to Salmonella minnesota followed by fusion with mouse myeloma cells. The use of a wide variety of glycolipids, including ganglioside lactones, enabled the p