Recombination and joining: different mea
β
Roland Kanaar; Jan Hoeijmakers
π
Article
π
1997
π
Blackwell Publishing
π
English
β 303 KB
DNA doubleβstrand breaks are very genotoxic lesions that can result in chromosome aberrations. The current view is that DNA doubleβstrand breaks are repaired most efficiently through homologous recombination in yeast and simple endβjoining in mammalian cells. However, recent experiments reveal that