Different clinical presentations of a lupus anticoagulant in the same family
β Scribed by Jolidon, R. -M. ;Knecht, H. ;Humair, L. ;Torrente, A.
- Publisher
- Springer-Verlag
- Year
- 1991
- Tongue
- English
- Weight
- 507 KB
- Volume
- 69
- Category
- Article
- ISSN
- 1432-1440
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Familial associations of the antiphospholipid antibody syndrome (APS) offer the opportunity to study genetic mechanisms of autoantibody production and disease, but are unusual. We identified a family, including identical twins and their mother, in which all members had systemic lupus erythematosus (
## Abstract The silica clotting time (SCT) is a phospholipidβdependent coagulation assay used for the laboratory diagnosis of lupus anticoagulant (LA) antibodies. The sensitivity and specificity of a new commercial SCT for identifying LA in patients who meet the clinical criteria for antiphospholip