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Differences inp16Gene Methylation and Expression in Benign and Malignant Ovarian Tumors

✍ Scribed by Lisa L McCluskey; Chen Chen; Erika Delgadillo; Juan C Felix; Laila I Muderspach; Louis Dubeau

Book ID
112247571
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
181 KB
Volume
72
Category
Article
ISSN
0090-8258

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## Abstract ## BACKGROUND. Methylation‐mediated suppression of detoxification, DNA repair, and tumor suppressor genes has been implicated in cancer development and progression. Studies also have indicated that concordant methylation of multiple genes (methylator phenotypes), rather than a single g