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Differences in transition state stabilization between thermolysin (EC 3.4.24.27) and neprilysin (EC 3.4.24.11)

✍ Scribed by Cynthia Marie-Claire; Emmanuel Ruffet; Gilles Tiraboschi; Marie-Claude Fournie-Zaluski


Book ID
117109900
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
107 KB
Volume
438
Category
Article
ISSN
0014-5793

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Selective Neurotensin-Derived Internally
✍ Vitor Oliveira; Marcelo Campos; Jefferson P. Hemerly; Emer S. Ferro; Antonio C.M πŸ“‚ Article πŸ“… 2001 πŸ› Elsevier Science 🌐 English βš– 86 KB

Internally quenched fluorescent peptides derived from neurotensin (pELYENKPRRPYIL) sequence were synthesized and assayed as substrates for neurolysin (EC 3.4.24.16), thimet oligopeptidase (EC 3.4.24.15 or TOP), and neprilysin (EC 3.4.24.11 or NEP). Abz-LYENKPRRPYILQ-EDDnp (where EDDnp is N-(2,4-dini