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Differences in the biotransformation of hexachlorobenzene (HCB) in male and female rats

✍ Scribed by E. Richter; G. Renner; J. Bayerl; M. Wick


Book ID
119020849
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
254 KB
Volume
10
Category
Article
ISSN
0045-6535

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## Abstract Hexachlorobenzene (HCB) is a persistent environmental contaminant which has been measured in human serum, fat, semen, and follicular fluid. In animal testing HCB has been shown to be a reproductive toxin. Discrepant results were obtained from prior studies concerning the effect of HCB t

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Hexachlorobenzene (HCB) residue levels in dosed rats (50.0 mg kg body wt. day-', n = 9 ) were significantly (P < 0.05) greater in the periovarian fat compared to the thyroid gland. Hexachlorobenzene residue levels were significantly (P < 0.05) greater in the thyroid versus the adrenal and ovary. Ova