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Differences in t cell receptor restriction fragment length polymorphisms in patients with rheumatoid arthritis

✍ Scribed by Sheana Whelan Funkhouser; Patrick Concannon; Patrick Charmley; Donna L. Vredevoe; Leroy Hood


Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
559 KB
Volume
35
Category
Article
ISSN
0004-3591

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The immunogenetic basis of pauciarticular-onset juvenile rheumatoid arthritis is unclear. We therefore analyzed the HLA and T cell receptor genes present in a clinically well-defined group of patients. We found that the DR8 haplotype contributes most of the HLAassociated risk, although alleles at ot