The serum levels of dehydroepiandrosterone (DHEA) and DHEA-sulfate (DHEA-S) were determined by radioimmunoassay in 38 patients with adult T-cell leukemia (ATL). Levels of serum DHEA and DHEA-S were also measured in 60 human T-lymphotropic virus type I (HTLV-I) carriers, and did not differ from those
Differences in Immune Functions between Human T-Lymphotropic Virus Type I Carriers and Patients with Adult T-Cell Leukemia/Lymphoma
β Scribed by Noriko Funai; Yoshinori Shimamoto; Shin-Ichi Yoshida; Yoshinori Nagai; Sachie Nakazato; Osamu Kohashi
- Book ID
- 112240856
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 869 KB
- Volume
- 80
- Category
- Article
- ISSN
- 1090-2341
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Adult T-cell leukernidlymphoma (ATL), a malignancy of mature CDCpositive lymphocytes, has been etiologically linked to the human retrovirus HTLV-I. Although a long latent period is suggested from migrant studies, little prospective information on the risk of developing ATL among persons with HTLV-I
## Abstract In a study of 7498 American men of Japanese ancestry in Hawaii, 26 incident cases of leukemia or nonβHodgkin's lymphoma were identified after a followβup period of 19 years. Two of the cases, who were brothers, were diagnosed with adult Tβcell leukemia/lymphoma (ATL). Both of these brot