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Differences in affinities of muscarinic acetylcholine receptor antagonists for brain and heart receptors

✍ Scribed by Raymond E. Gibson; Waclaw J. Rzeszotarski; William C. Eckelman; Elaine M. Jagoda; Douglas J. Weckstein; Richard C. Reba

Book ID
115776713
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
607 KB
Volume
32
Category
Article
ISSN
0006-2952

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πŸ“œ SIMILAR VOLUMES

Molecular connectivity study of muscarin
Molecular connectivity study of muscarinic receptor affinity of acetylcholine antagonists
✍ Lemont B. Kier; Lowell H. Hall πŸ“‚ Article πŸ“… 1978 πŸ› John Wiley and Sons 🌐 English βš– 539 KB

A correlation between three molecular connectivity indexes and the muscarinic receptor affinity of 104 acetylcholine antagonists was found. Analysis of structure from these indexes reveals not only the importance of the onium and the bulky portions of the molecule but also their virtual independence