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Difference circular dichroism studies of copper and nickel binding to d-penicillamine in the presence of human serum albumin

✍ Scribed by Parekkat Mohanakrishnan; Colin F. Chignell

Book ID
115778197
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
338 KB
Volume
34
Category
Article
ISSN
0006-2952

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The reversible binding of ethacrynic acid was characterized by a difference circular dichroism method. A 2/1 stoichiometry was determined for the [drug]/[HSA] (human serum albumin) complex. The reversible binding of ethacrynic acid to HSA determines direct competition with ligands that selectivity b