✦ LIBER ✦

Dietary protein: a trigger of insulin-dependent diabetes in the BB rat?

✍ Scribed by R. B. Elliott; J. M. Martin

Publisher: Springer
Year: 1984
Tongue: English
Weight: 246 KB
Volume: 26
Category: Article
ISSN: 0012-186X
DOI: 10.1007/bf00283653

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✦ Synopsis

Animals from a colony of spontaneously diabetic insulin-dependent BB rats were fed from weaning with semi-synthetic diets in which natural proteins were replaced by l-amino acids with or without the addition of either milk or wheat proteins. The normal 50% incidence of diabetes in the colony was reduced to 15% in rats fed the basic semi-synthetic diet, while it was 35% and 52% when supplemented with gluten or milk, respectively. Thus, dietary factors might precipitate the expression of the disease.

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